Intrinsic Imaging Publishes Its Metrics Champion Consortium Imaging Performance Targets

Intrinsic Imaging Publishes Its Metrics Champion Consortium Imaging Performance Targets

Bolton, MA, San Antonio, TX September 29, 2010

Intrinsic Imaging LLC, an imaging core lab, publishes today its Metrics Champion Consortium Imaging Performance Targets.

“Intrinsic Imaging’s business model is entirely focused on optimizing the management and analysis of medical images during Phase I-IV clinical trials. Without compromising quality or regulatory compliance, we are able to achieve unprecedented operational targets due to our unique technology, our optimized business model and our in depth radiology expertise across all therapeutic areas.” said Todd A. Joron, BSc, MBA, President and COO, Intrinsic Imaging.

Intrinsic Imaging is a corporate sponsor of the Metrics Champion Consortium (MCC). The MCC’s mission is to develop performance metrics within the biotechnology and pharmaceutical industry with the intent to jointly encourage performance improvement, effectiveness, efficiency, and appropriate levels of controls for both Sponsors and Service Providers in support of the drug development process. The MCC Imaging Performance Metrics Steering Committee recently released V1.0 of its imaging metrics.

“With our team of more than sixty sub-specialized, board-certified radiologists, and through use of our innovative Clinical Imaging Management System from Merge Healthcare, we are able to streamline our medical imaging operations.” said Todd Tibbetts, M.D., Ph.D., Medical Director, Oncology at Intrinsic. “We are thereby able to manage medical images much more effectively and provide radiology review of images to Sponsors in a much shorter time period.”

For comparative purposes, Table 1 outlines select operational targets related to imaging acquisition, processing, queries and submissions. As presented, Intrinsic Imaging’s target metrics are significantly more aggressive than current MCC targets.
Intrinsic executives attribute these material differences to their unique ability to readily implement new best-of-breed technologies to enable faster and more cost effective management, analysis and reporting of medical images in clinical trials.

Table 2 provides a complete set of Intrinsic Imaging’s current operational targets. Intrinsic reports all of its MCC imaging metrics for each clinical trial and these are provided at no incremental cost to the Sponsor. Further, to demonstrate the Company’s commitment to attaining these targets, Intrinsic Imaging provides all Sponsors with service level agreements (SLAs) identifying these metrics as appropriate.

Table 1 – Selected Intrinsic Imaging Performance Targets vs MCC

Metrics Champion Consortium (MCC)
Imaging Performance Targets

MCC
Target
(days)

Intrinsic
Target
(days)

Intrinsic Difference
(days)

Intrinsic Difference
(%)

Average number of calendar days from image receipt to initial feedback to site

7

2

-5

-71%

Average number of calendar days from image QC complete to reporting of eligibility results

5

2

-3

-60%

Average number of calendar days from image receipt to ready for independent (radiologist) review

20

2

-18

-90%

Average number of calendar days an imaging query is outstanding

10

3

-7

-70%

Average number of calendar days from last patient reviewed (by a radiologist) to delivery of dataset

14

2

-12

-86%

 

Table 2 – Intrinsic Complete MCC v.1.0 Imaging Performance Targets

#

MCC CategoryMCC Metric Title

Intrinsic Target

1

FinancialAverage percentage of variance in the imaging budget

< 5%

2

Contract SignatureAverage number of calendar days from imaging study award to contract signature

Depends on client . Intrinsic ready in < 5 days

3

Site Start-UpPercentage of sites qualified vs. actual

>85%

4

Site Start-UpAverage number of calendar days from site designated ready to first date of image receipt

Protocol and site dependent

5

Image AcquisitionAverage number of calendar days from image acquisition to image receipt

3 days

6

Image AcquisitionAverage number of calendar days from image receipt to initial feedback to site

2 days

7

Image ProcessingAverage number of calendar days from image QC complete to reporting of eligibility results

2 days

8

Image ProcessingAverage number of calendar days from image receipt to ready for independent (radiology) review

2 days

9

Image ProcessingAverage number of calendar days from when the image is designated for review to completion of the review

3 days

10

Image QualityPercentage of suboptimal (but evaluable) images

< 5%

11

Image QualityPercentage of non-evaluable images versus total received

< 10%

12

Image QualityPercentage of non-evaluable baseline images

< 5%

13

Missing ImagingPercentages of missing imaging visits

< 3%

14

Image QueriesPercentage of site queries

< 10%

15

Image QueriesAverage number of calendar days an imaging query is outstanding

3 days

16

Export SubmissionAverage number of calendar days from last patient reviewed to delivery of dataset

2 days

17

Export SubmissionAverage number of calendar days from original estimate to actual for export submission

< 10%

18

Independent Review CharterNumber of weeks to develop and write independent review charter

< 1 week

19

Acquisition Protocol RobustnessNumber of image acquisition technique-related amendments per modality per protocol

Protocol dependent

 

About Intrinsic Imaging LLC
Located in Bolton, Massachusetts and San Antonio, Texas, Intrinsic Imaging is an FDA audited, ISO 9001, ISO 13485, ISO 22301 and ISO 27001 certified and GAMP5 compliant medical imaging core lab specializing in providing imaging core lab services for clinical trials. With its team of more than seventy board-certified fellowship trained radiologists, robust and scalable clinical imaging technologies and its ISO certified quality management systems, Intrinsic Imaging is ideally positioned to provide unprecedented imaging core lab services around the world.